Griffin Canning to start; Germán Márquez to IL

The San Diego Padres activated right-handed starter Griffin Canning from the injured list Sunday morning to start in the final game in the series against the Chicago White Sox. Right-hander Randy Vásquez, slated to start on Sunday, will be pushed back to Monday in San Francisco.

The corresponding move for the Padres is to place right-handed starter Germán Márquez on the 15-day injured list with right forearm nerve inflammation, retroactive to May 2. Márquez started on Friday against the White Sox, allowing seven runs on five hits and five walks in five innings pitched. He also got two strikeouts while increasing his ERA to 5.76.

Canning injured his Achilles tendon while pitching for the New York Mets last season. He began the 2026 season with Triple-A El Paso and started five games. He threw 62 pitches in his last start on Tuesday, allowing three hits with no earned runs, allowing a walk with four strikeouts. It was expected that Canning would complete his rehab today with El Paso but is joining the Padres instead.

The injury to Márquez pushes his start to San Diego and Canning could go 70-80 pitches with a natural progression from his last start. Canning features six pitches with his four-seam fastball and slider being dominant. His pitching is ground-ball heavy but he has the repertoire to get swing-and-miss as well.

Márquez, who signed with the Padres in the offseason, underwent Tommy John surgery in 2024 and has struggled to return to his former effectiveness before the surgery. He has started six games for the Padres and has a 3-2 record with his 5.76 ERA. He features a knuckle curve 40% of the time and his 94 mph four-seam fastball 36% of the time. He also flashes a sinker, slider and changeup.

Márquez had two starts allowing no earned runs but allowed at least four earned runs in all the other outings before allowing the seven runs on May 1.