March Madness odds: NCAA tournament favorites entering Sweet 16

March Madness odds: NCAA tournament favorites entering Sweet 16

Tickets have been punched for the Sweet 16 as the Men's NCAA Tournament wrapped up the opening rounds on Sunday night. While there were plenty of bracket-busting upsets, the headliner of the weekend was No. 1 Florida falling to No. 9 seed Iowa, creating an unexpected group heading off to next weekend.

The oddmakers still favor one team, though, with several perennial basketball powers following closely behind the top spot.

Which teams are the current favorites to end the NCAA tournament as champions?

Here are the March Madness odds as the NCAA tournament moves into the Sweet 16…

16. Texas Longhorns

Mar 21, 2026; Portland, OR, USA; Texas Longhorns forward Nic Codie (10) reacts after defeating the Gonzaga Bulldogs during a second round game of the men's 2026 NCAA Tournament at Moda Center.

NCAA tournament odds: +25000

15. Alabama Crimson Tide

Mar 22, 2026; Tampa, FL, USA; Alabama Crimson Tide guard Houston Mallette (95) celebrates after a play against the Texas Tech Red Raiders in the first half during a second round game of the men's 2026 NCAA Tournament at Benchmark International Arena.

NCAA tournament odds: +10000

T-13. Iowa Hawkeyes

Mar 22, 2026; Tampa, FL, USA; Iowa Hawkeyes forward Alvaro Folgueiras (7) makes a go-ahead three-point basket against the Florida Gators late in the second half during a second round game of the men's 2026 NCAA Tournament at Benchmark International Arena

NCAA tournament odds: +6600

T-13. Tennessee Volunteers

Mar 22, 2026; Philadelphia, PA, USA; Tennessee Volunteers forward J.P. Estrella (13) reacts after defeating the Virginia Cavaliers during a second round game of the men's 2026 NCAA Tournament at Xfinity Mobile Arena.

NCAA tournament odds: +6600

T-11. Nebraska Cornhuskers

Nebraska's Jamarques Lawrence (10) goes up for a basket as Vanderbilt's Tyler Tanner (3), Duke Miles (2) and Jalen Washington (13) defend during a second-round game in the NCAA men's basketball tournament.

NCAA tournament odds: +4000

T-11. Arkansas Razorbacks

Mar 21, 2026; Portland, OR, USA; High Point Panthers forward Terry Anderson (5) drives against Arkansas Razorbacks forward Malique Ewin (12) and forward Billy Richmond III (24) in the second half during a second round game of the men's 2026 NCAA Tournament

NCAA tournament odds: +4000

T-9. Michigan State Spartans

Mar 21, 2026; Buffalo, NY, USA; Michigan State Spartans center Carson Cooper (15) dunks the ball against the Louisville Cardinals during the second half of the second round game of the men's 2026 NCAA Tournament at Keybank Center.

NCAA tournament odds: +3000

T-9. St. John's Red Storm

Mar 22, 2026; San Diego, CA, USA; St. John's Red Storm guard Dylan Darling (0) celebrates after defeating the Kansas Jayhawks in the second half during a second round game of the men's 2026 NCAA Tournament at Viejas Arena.

NCAA tournament odds: +3000

8. UConn Huskies

Mar 22, 2026; Philadelphia, PA, USA; UConn Huskies forward Alex Karaban (11) and guard Braylon Mullins (24) react in the second half during a second round game of the men's 2026 NCAA Tournament at Xfinity Mobile Arena.

NCAA tournament odds: +2800

7. Iowa State Cyclones

Mar 22, 2026; St. Louis, MO, USA; Iowa State Cyclones guard Killyan Toure (27) reacts during the second half against the Kentucky Wildcats during a second round game of the men's 2026 NCAA Tournament at Enterprise Center.

NCAA tournament odds: +1700

6. Illinois Fighting Illini

GREENVILLE, SOUTH CAROLINA - MARCH 21: Keaton Wagler #23 of the Illinois Fighting Illini shoots the ball against Brandon Jennings #0 and Lazar Djokovic #17 of the VCU Rams during the second half in the second round of the 2026 NCAA Men's Basketball Tournament

NCAA tournament odds: +1400

5. Purdue Boilermakers

Purdue Boilermakers guard Fletcher Loyer (2) reacts after scoring a three-point field goal against the Miami Hurricanes during a NCAA Tournament second round game Sunday, March 22, 2026, at Enterprise Center in St. Louis. Purdue defeated Miami 79-69.

NCAA tournament odds: +1200

4. Houston Cougars

Houston's Chris Cenac Jr. (5) cheers during a second-round game in the NCAA men's basketball tournament between Houston Cougars and Texas A&M Aggies at Paycom Center in Oklahoma City, Saturday March 21, 2026.

NCAA tournament odds: +700

3. Duke Blue Devils

Duke Blue Devils forward Maliq Brown (6) dunks near TCU Horned Frogs guard Jayden Pierre (1) March 21, 2026 during the second half of the NCAA Men’s Basketball Tournament second round East Region game at the Bon Secours Wellness Arena in Greenville, South Carolina.

NCAA tournament odds: +425

2. Arizona Wildcats

Mar 22, 2026; San Diego, CA, USA; Arizona Wildcats guard Brayden Burries (5) reacts in the second half against the Utah State Aggies during a second round game of the men's 2026 NCAA Tournament at Viejas Arena.

NCAA tournament odds: +325

1. Michigan Wolverines

Mar 21, 2026; Buffalo, NY, USA; Michigan Wolverines forward Oscar Goodman (5) shoots the ball while defended by Saint Louis Billikens guard Kellen Thames (0) and guard Amari McCottry (4) in the second half during a second round game of the men's 2026 NCAA Tournament

NCAA tournament odds: +300

This article originally appeared on The List Wire: March Madness look at NCAA tournament favorites ahead of Sweet 16